Program

Timetable

Timetable

General Session

Honor Invited Lecture

December 9 (Mon.) 17:30-18:30  Room A (2F Main Convention Hall)

Next-gen drug development with human organoid technology

  • Chair : Hideki Hirabayashi
    Drug Metabolism and Pharmacokinetics Research Laboratories,Takeda Pharmaceutical Company Limited
  • Speaker : Takanori Takebe
    Institute of Research, Tokyo Medical and Dental University / Center for Stem Cell and Organoid Medicine, Cincinnati Children's Hospital Medical Center

Invited Lecture 1

December 10 (Tue.) 13:15-14:15  Room A (2F Main Convention Hall)

Pharmacometrics and Systems Modeling in Hematological Malignancies

  • Chair : Yasuhisa Nagasaka
    Quantitative Systems Pharmacology, Analysis & Pharmacokinetics Research Laboratories, Astellas Pharma Inc.
  • Speaker : Donald E. Mager
    University at Buffalo, The State University of New York

Invited Lecture 2

December 11 (Wed.) 13:15-14:15  Room A (2F Main Convention Hall)

Integration of innovative mechanistic test systems for chemical safety testing: the EUToxRisk strategy

  • Chair : Kouichi Yoshinari
    Department of Molecular Toxicology, School of Pharmaceutical Sciences, University of Shizuoka
  • Speaker : Bob van de Water
    Leiden University, Leiden Academic Centre for Drug Research

Invited Lecture 3 (Symposium 8)

December 12 (Thu.) 9:30-11:45  Room C (2F Conference room201)

  • Organizers / Chairs : Amin Rostami-Hodjegan
    Centre for Applied Pharmacokinetic Research, University of Manchester, UK / Certara, Princeton, New Jersey, USA.
  •  Shuichi Sekine
    Shiseido Co. Ltd., Global Innovation Center
  •  Yasuhisa Nagasaka
    Quantitative Systems Pharmacology, Analysis & Pharmacokinetics Research Labs, Astellas Pharma Inc.

IL3 (SY-08-04) "Merging human microphysiological systems with quantitative systems pharmacology for in vitro in vivo translation"

  • Speaker : Murat Cirit
    Javelin Biotech, Inc., USA.

President’s Lecture

December 9 (Mon.) 18:30-19:00  Room A (2F Main Convention Hall)

Message from the JSSX president: Current topics in societal impact of physiologically based kinetic modeling in cutting-edge sciences

  • Chair : Kenji Tabata
    Analysis & Pharmacokinetics Research Laboratories, Astellas Pharma Inc.
  • Speaker : Hiroshi Yamazaki
    Laboratory of Drug Metabolism and Pharmacokinetics, Showa Pharmaceutical University

New President's Lecture

December 11 (Wed.) 15:50-16:10  Room A (2F Main Convention Hall)

Message from the new president

  • Chair : Kenji Tabata
    Analysis & Pharmacokinetics Research Laboratories, Astellas Pharma Inc.
  • Speaker : Yoshiro Saito
    Division of Medicinal Safety Science, National Institute of Health Sciences

Symposium 1(Drug Metabolism and Drug Induced Toxicity DIS 1)

December 10 (Tue.) 9:30-11:45  Room B (2F Convention hall 200)

Pharmacokinetics and toxicity development in the skin

  • Organizers : Miki Nakajima
    Drug Metabolism and Toxicology, Faculty of Pharmaceutical Sciences, Kanazawa University
  •  Kousei Ito
    Laboratory of Biopharmaceutics, Graduate School of Pharmaceutical Sciences, Chiba University
  • Organizer / Chair : Satoshi Yamaori
    Department of Pharmacy, Shinshu University Hospital
  • Chair : Shigeki Aoki
    Laboratory of Biopharmaceutics, Graduate School of Pharmaceutical Sciences, Chiba University
  • SY-01-01 "The interaction of tyrosine kinase inhibitors with keratinocytes and its dermal toxicity in humans"
  • Speaker : Yusuke Masuo
    Faculty of Pharmacy, Institute of Medical, Pharmaceutical, and Health Sciences, Kanazawa University
  • SY-01-02 "Drug-induced phototoxicity: prediciction and de-risking"
  • Speaker : Satomi Onoue
    Laboratory of Biopharmacy, School of Pharmaceutical Sciences, University of Shizuoka
  • SY-01-03 "Susceptibility to serious skin and subcutaneous tissue disorders and skin tissue distribution of sodium-dependent glucose co-transporter type 2 (SGLT2) inhibitors"
  • Speaker : Toshiyuki Sakaeda
    Department of Pharmacokinetics, Kyoto Pharmaceutical University
  • SY-01-04 "Role of STAT3 in hand-foot skin reaction induced by multi-targeted tyrosine kinase inhibitors"
  • Speaker : Kazuhiro Yamamoto
    Department of Pharmacy, Kobe University Hospital

Symposium 2 (Microphysiological System DIS)

December 10 (Tue.) 14:30-17:00  Room A (2F Main Convention Hall)

Evolution of in vitro barrier tissue models by microphysiological systems

  • Organizer / Chair : Kazuhiro Tetsuka
    Analysis & Pharmacokinetics Research Laboratories, Astellas Pharma Inc.
  • Chair : Masatoshi Tomi
    Faculty of Pharmacy, Keio University
  • SY-02-01 "Development of a conditionally immortalized cell-based human blood-brain barrier model for CNS drug development"
  • Speaker : Tomomi Furihata
    Department of Clinical Pharmacy and Experimental Therapeutics, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences
  • SY-02-02 "Engineering of iPSC-based Organs-on-Chips to model intestinal function"
  • Speaker : Yu-suke Torisawa
    The Hakubi Center for Advanced Research & Department of Micro Engineering, Kyoto University
  • SY-02-03 "Fabrication of epithelial and endothelial barrier tissue models utilizing a collagen vitrigel membrane and their application to the system for predicting ADME/Tox of chemicals"
  • Speaker : Toshiaki Takezawa
    Institute of Agrobiological Sciences, National Agriculture and Food Research Organization
  • SY-02-04 "Nephrotoxicity, kidney transport, and disease modelling on organotypic kidney-on-a-chip models"
  • Speaker : Henriëtte Lanz
    MIMETAS B.V.
  • SY-02-05 "Development of proximal tubule-on-a-chip: fluid shear stress stimulates MATE2-K expression via Nrf2 pathway activation"
  • Speaker : Yasunori Fukuda
    Rare Disease Medical, Sanofi K.K.

Symposium 3 (DDS DIS)

December 10 (Tue.) 14:30-17:00  Room C (2F Conference room201)

Drug Delivery System Targeting to Blood Vessels

  • Organizer / Chair : Tatsuhiro Ishida
    Graduate School of Biomedical Sciences, Tokushima University
  • Chair : Masanori Tachikawa
    Graduate School of Biomedical Sciences, Tokushima University
  • SY-03-01 "Passive tumor targeting via EPR effect"
  • Speaker : Tatsuhiro Ishida
    Graduate School of Biomedical Sciences, Tokushima University
  • SY-03-02 "Heterogeneity of tumor blood vessels"
  • Speaker : Kyoko Hida
    Vascular Biology and Molecular Pathology, Graduate School of Dental Medicine, Hokkaido University
  • SY-03-03"Targeting of albumin to pancreatic cancer via endogenous albumin transport system"
  • Speaker : Yu Ishima
    Institute of Biomedical Sciences, Tokushima University
  • SY-03-04 "Blood-brain barrier-permeable proteins and transport characteristics in brain endothelial cells"
  • Speaker : Masanori Tachikawa
    Graduate School of Biomedical Sciences, Tokushima University
  • SY-03-05 "Microfluidic device for reproduction of in vivo microenvironment with three-dimensional vascular structure"
  • Speaker : Kenichi Funamoto
    Institute of Fluid Science, Tohoku University

Symposium 4 (Systems Pharmacology DIS)

December 11 (Wed.) 9:30-11:45  Room A (2F Main Convention Hall)

Systems modeling in next 10 years

  • Organizer : Yasuhisa Nagasaka
    Quantitative Systems Pharmacology, Analysis & Pharmacokinetics Research Laboratories, Astellas Pharma Inc.
  • Chairs : Koji Chiba
    Laboratory of Clinical Pharmacology, Yokohama University of Pharmacy
  •  Takayo Ueno
    Department of Clinical Pharmacology Strategy, Bristol-Myers Squibb K.K.
  • SY-04-01 "Overview of systems modeling development during the past 10 years" (tentative)
  • Speaker : Donald E. Mager
    University at Buffalo, The State University of New York
  • Chairs : Hiroto Hatakeyama
    Laboratory of Clinical Pharmacology and Pharmacometrics, Graduate School of Pharmaceutical Sciences, Chiba University
  •  Tsuyoshi Minematsu
    Quantitative Systems Pharmacology, Analysis & Pharmacokinetics Research Laboratories, Astellas Pharma Inc.
  • SY-04-02 "Drug repositioning and target finding based on clinical evidence"
  • Speaker : Shuji Kaneko
    Department of Molecular Pharmacology, Graduate School of Pharmaceutical Sciences, Kyoto University
  • Chairs : Teruki Hamada
    Axcelead Drug Discovery Partners, Inc.
  •  Ryoko Sawamura
    Clinical Pharmacology Department, Daiichi Sankyo Co., Ltd.
  • SY-04-03"Virtual clinical trial using QSP model and its case study"
  • Speaker : Takuya Miyano
    Biomarker & Translational Research Department, Daiichi Sankyo Co., Ltd.
  • Chairs : Masayo Oishi
    Quantitative Systems Pharmacology, Analysis & Pharmacokinetics Research Laboratories, Astellas Pharma Inc.
  •  Yasuhisa Nagasaka
    Quantitative Systems Pharmacology, Analysis & Pharmacokinetics Research Laboratories, Astellas Pharma Inc.
  • SY-04-04 "Integrated use of QSP (PBPK) and MPS; Current status, issues and future perspectives"
  • Speaker : Amin Rostami-Hodjegan
    Centre for Applied Pharmacokinetic Research, University of Manchester, UK / Certara, Princeton, New Jersey, USA.

Symposium 5 (Drug Metabolism and Drug Induced Toxicity DIS 2)

December 11 (Wed.) 9:30-11:45  Room C (2F Conference room201)

Mechanism and prediction of down-regulation of drug-metabolizing enzymes

  • Organizer : Miki Nakajima
    Drug Metabolism and Toxicology, Faculty of Pharmaceutical Sciences, Kanazawa University
  • Organizers / Chairs : Kaoru Kobayashi
    Laboratory of DDS Design and Drug Disposition, Graduate School of Pharmaceutical Sciences, Chiba University
  •  Seigo Sanoh
    Department of Neurochemistry and Environmental Health Sciences, Graduate School of Biomedical and Health Sciences, Hiroshima University
  • SY-05-01 "Evaluation of in vitro CYP1A2 down-regulation using cryopreserved human hepatocytes"
  • Speaker : Chihiro Ishida
    Graduate School of Biomedical and Health Sciences, Hiroshima University / Pharmacokinetics and Safety Assessment Dept., Discovery Research Labs, Nippon Shinyaku Co., Ltd.
  • SY-05-02 "Cytochrome P450 induction and down-regulation in human hepatocytes at the lead-optimization stage of drug development"
  • Speaker : Mika Nagai
    Department of Pharmacokinetics and Safety, Drug Research Center, Kaken Pharmaceutical Co., Ltd.
  • SY-05-03"Prediction and analysis for down-regulation of drug metabolizing enzymes: Utility of 3D-cultured cells"
  • Speaker : Kaoru Kobayashi
    Laboratory of DDS Design and Drug Disposition, Graduate School of Pharmaceutical Sciences, Chiba University
  • SY-05-04 "Regulation of human drug metabolizing enzymes by two prevalent post-transcriptional modifications, A-to-I editing and methylation of adenosine"
  • Speaker : Masataka Nakano
    Drug Metabolism and Toxicology, Faculty of Pharmaceutical Sciences, Kanazawa University
  • SY-05-05 "The influence of drug administration during pregnancy evaluated from the pharmacokinetic analysis of embryo"
  • Speaker : Wataru Ochiai
    Department of Clinical Pharmacokinetics, School of Pharmacy and Pharmaceutical Sciences, Hoshi University

Symposium 6 (Drug Metabolism and Drug Induced Toxicity DIS 3)

December 12 (Thu.) 9:45-11:45  Room A (2F Main Convention Hall)

Challenges of ADME and safety research for "beyond rule of 5" chemical drug discovery

  • Organizer : Miki Nakajima
    Drug Metabolism and Toxicology, Faculty of Pharmaceutical Sciences, Kanazawa University
  • Organizers / Chairs : Shin-ichi Inoue
    Drug Metabolism & Pharmacokinetics Research Laboratories, Daiichi Sankyo Co., Ltd
  •  Tetsuya Nakagawa
    Preclinical Research Unit, Sumitomo Dainippon Pharma Co.,Ltd.
  • SY-06-01 "Drug discovery approach to challenging targets with ligands beyond Lipinski’s rule-Improvement of R&D productivity by AI-based activity prediction system-"
  • Speaker : Hirotsugu Komatsu
    Interprotein Corporation
  • SY-06-02 "Development of orally delivered biopharmaceuticals using the small intestine-permeable cyclic peptide"
  • Speaker : Shingo Ito
    Department of Pharmaceutical Microbiology, Faculty of Life Sciences, Kumamoto University
  • SY-06-03 "Contribution of DMPK researcher on antisense oligonucleotide drug discovery and development: A preclinical pharmacokinetics study"
  • Speaker : Syunsuke Yamamoto
    Drug Metabolism & Pharmacokinetics Research Laboratories, Research, Takeda Pharmaceutical Company Limited
  • SY-06-04 "Mechanistic investigation of RNaseH1-dependent hepatotoxicity caused by gapmer antisense oligonucleotides"
  • Speaker : Ayahisa Watanabe
    Research Laboratory for Development, Pharmaceutical Research & Development Division, Shionogi & Co., Ltd.

Symposium 7 (BioAnalysis and BioImaging DIS)

December 12 (Thu.) 9:45-11:45 Room B (2F Convention hall 200)

Advanced analytical techniques and technologies for pharmacokinetic evaluation of new modality drugs

  • Chair : Kosuke Saito
    Section Chief, Division of Medical Safety Science, National Institute of Health Sciences
  • Organizer / Chair : Junji Komaba
    Pharmacokinetic Research Laboratories, Ono Pharmaceutical Co.,Ltd
  • SY-07-01 "In vivo fluorescence imaging of transplanted stem cells labeled with quantum-nano materials for regenerative medicine"
  • Speaker : Hiroshi Yukawa
    Institute of Nano-Life-Systems, Institutes of Innovation for Future Society, Nagoya University
  • SY-07-02 "In vivo PET imaging and Radiolabeling techniques of Antibodies and Cells for therapeutic biologics"
  • Speaker : Takanori Sasaki
    Collaborative Research Center for Okayama Medical Innovation Center (OMIC), Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
  • SY-07-03 "Recent progress of bioanalysis of oligonucleotides and consideration on regulatory interaction"
  • Speaker : Takefumi Gemba
    Clinical & Regulatory Strategy, Covance Japan Co., Ltd.
  • SY-07-04 "Bioanalytical challenges for the quantification of total and free therapeutic antibodies: Points to consider for the PK/PD evaluation"
  • Speaker : Ichio Onami
    Research division, Fuji-Gotemba Laboratories, Chugai Pharmaceutical Co., Ltd.

Symposium 8 (MPS & SP DIS Joint)

December 12 (Thu.) 9:30-11:45  Room C (2F Conference room201)

Impact of complemental use of Micro-Physiological Systems and Systems Modeling with in vitro-in vivo translation on drug discovery and development -current status and future perspective-

  • Organizers / Chairs : Amin Rostami-Hodjegan
    Centre for Applied Pharmacokinetic Research, University of Manchester, UK / Certara, Princeton, New Jersey, USA.
  •  Shuichi Sekine
    Shiseido Co. Ltd., Global Innovation Center
  •  Yasuhisa Nagasaka
    Quantitative Systems Pharmacology, Analysis & Pharmacokinetics Research Labs, Astellas Pharma Inc.
  • SY-08-01 "Translation from In Vitro to In Vivo: Why it is not that simple?"
  • Speaker : Amin Rostami-Hodjegan
    Centre for Applied Pharmacokinetic Research, University of Manchester, UK / Certara, Princeton, New Jersey, USA.
  • SY-08-02 "Gut/liver microphysiological system for quantitative analysis of drug sequential metabolism and interorgan interaction"
  • Speaker : Yukio Kato
    Department of Molecular Pharmacotherapeutics, Faculty of Pharmacy, Kanazawa University
  • SY-08-03 "Prediction of Transporter-Mediated Disposition Using Primary Human Hepatocytes"
  • Speaker : Emi Kimoto
    ADME Sciences, Medicine Design, Pfizer Inc., Groton, CT, USA
  • SY-08-04 (IL 3) "Merging human microphysiological systems with quantitative systems pharmacology for in vitro in vivo translation (IVIVT)"
  • Speaker : Murat Cirit
    Javelin Biotech, Inc., USA.

Symposium 9 (Drug Efficacy and Safety DIS)

December 12 (Thu.) 9:30-11:45  Room D (1F conference room101)

System biological approaches for development of pharmacological and diagnostic biomarkers

  • Organizer / Chair : Satoru Koyanagi
    Kyushu University, Faculty of Pharmaceutical Sciences
  • Chair : Masanori Tachikawa
    Tokushima University, Institute of Biomedical Sciences
  • SY-09-01 "Finding novel aspects of drugs with profile data analysis and possibilities utilizing the outcomes for understanding diseases"
  • Speaker : Tadahaya Mizuno
    Graduate School of Pharmaceutical Sciences, The University of Tokyo
  • SY-09-02 "Development and application of arrhythmic hazard map under multiple ion channel block using heart simulator"
  • Speaker : Jun-Ichi Okada
    Future Center Initiative, The University of Tokyo
  • SY-09-03 "Linkage between metabolome properties and cancer drug resistance"
  • Speaker : Hiromi Sato
    Clinical Pharmacology and Pharmacometrics, Graduate School of Pharamceutical Sciences, Chiba University
  • SY-09-04 "Biomarker Search for Major Depressive Disease by Metabolomics Approach"
  • Speaker : Dongchon Kang
    Department of Clinical Chemistry and Laboratory Medicine, Kyushu University Graduate School of Medical Sciences
  • SY-09-05 "Exploration of the biomarkers for kidney diseases using chiral amino acid metabolomics"
  • Speaker : Tomonori Kimura
    National Institutes of Biomedical Innovation, Health and Nutrition (NIBIOHN)

Symposium 10 (Regulation DIS)

December 12 (Thu.) 13:15-15:45  Room A (2F Main Convention Hall)

Physiologically based pharmacokinetic model: Utilization of PBPK modeling and simulation in the drug development or approval review and current status on regulatory documents in the US, EU and Japan

  • Organizer : Naomi Nagai
    Musashino University
  • Chairs : Akihiro Ishiguro
    Office of Research Promotion, Center for Regulatory Science Pharmaceuticals and Medical Devices Agency (PMDA)
  •  Daisuke Nakai
    Daiichi Sankyo Co., Ltd.
  • SY-10-01 "Utilizing drug information from physiologically-based Pharmacokinetic modeling"
  • Speaker : Kosuke Doki
    Department of Pharmaceutical Sciences, Faculty of Medicine, University of Tsukuba
  • SY-10-02 "Current Status and Future Challenges in Quantitative Prediction by Physiologically-Based Pharmacokinetic Modeling: Case Studies of New Molecule Entities"
  • Speaker : Shinji Yamazaki
    Pharmacokinetics, Dynamics & Metabolism, Pfizer Worldwide Research & Development, San Diego, California, USA
  • SY-10-03 "PK and DDI evaluation in alignment with the EMA guideline document on qualification of PBPK modeling and simulations"
  • Speaker : Kenichi Umehara
    Pharmaceutical Sciences, Roche Pharmaceutical Research and Early Development, Roche Innovation Center Basel
  • SY-10-04 "Current state of new drug review utilizing PBPK modeling and developing PBPK modeling guideline"
  • Speaker : Shinichi Kijima
    Pharmaceuticals and Medical Devices Agency, Office of Advanced Evaluation with Electronic Data

Symposium 11 (New modality DIS)

December 12 (Thu.) 13:15-15:45  Room C (2F Conference room201)

Contribution of Pharmacokinetic Approach to Peptide-based Therapeutics

  • Organizer / Chair : Takashi Kuwabara
    Laboratory of Biologics evaluation,Yokohama University of Pharmacy
  • Chair : Kazuhisa Ozeki
    Research Division, Chugai Pharmaceutical Co., Ltd
  • SY-11-01 "Pharmacokinetic control of bioactive peptides upon DDS approaches"
  • Speaker : Satomi Onoue
    Laboratory of Biopharmacy, School of Pharmaceutical Sciences, University of Shizuoka
  • SY-11-02 "Introduction of a modified membrane permeability assay considering intracellular distribution"
  • Speaker : Yuji Sakurai
    Laboratory of Biopharmacy, School of Pharmaceutical Sciences, University of Shizuoka
  • SY-11-03 "Crucial Transporters for Cyclic Peptide Drugs Discovery"
  • Speaker : Yasuto Kido
    Drug Metabolism & Pharmacokinetics, Research Laboratory for Development, Shionogi & Co.,Ltd
  • SY-11-04 "Peptide-based Carriers for drug delivery into cells and brain"
  • Speaker : Toshihide Takeuchi
    Osaka University Graduate School of Medicine

Symposium 12 (Transporter DIS)

December 12 (Thu.) 13:15-15:45  Room D (1F conference room101)

Transporters at the crossroads of physiology, pathology, and drug development

  • Organizer / Chair : Katsuhisa Inoue
    School of Pharmacy, Tokyo University of Pharmacy and Life Sciences
  • Chair : Kazuya Maeda
    Graduate School of Pharmaceutical Sciences, The University of Tokyo
  • SY-12-01 "The xenobiotic transporter Mdr1 directs T cell adaptation to bile acids in the ileum"
  • Speaker : Hisako Kayama
    Institute for Advanced Co-Creation Studies, Osaka University
  • SY-12-02 "Blood-brain barrier P-glycoprotein activation as a new potential therapy of brain infarct"
  • Speaker : Yasuo Uchida
    Graduate School of Pharmaceutical Sciences, Tohoku University
  • SY-12-03 "Mechanism of the uptake of naked single-stranded oligonucleotides into living cells"
  • Speaker : Masayuki Takahashi
    Research Institute for Healthy Living, Niigata University of Pharmacy and Applied Life Sciences
  • SY-12-04 "Clinical impact on the role of parathyroid hormone in regulating ABCG2 and CYP3A"
  • Speaker : Hiroshi Watanabe
    Department of Biopharmaceutics, Graduate School of Pharmaceutical Sciences, Kumamoto University

Space drug discovery Symposium

December 10 (Tue.) 9:30-11:45  Room A (2F Main Convention Hall)

Mouse Mission in "Kibo" / International Space Station (ISS) and Perspective on Pharmacokinetics in Space-Drug Discovery

  • Organizer : Hiroshi Fushiki
    Astellas Pharma Inc., Drug Discovery Research,Analysis & Pharmacokinetic Research Labs.
  • Organizers / Chairs : Satoru Takahashi
    Transborder Medical Research Center, Fuclty of Medicine, University of Tsukuba
  •  Dai Shiba
    JEM Utilization Center, Human Spaceflight Technology Directorate, Japan Aerospace Exploration Agency (JAXA)
  • SSY-01 "Development of new experimental platform to elucidate the impacts of micro/partial gravity on mice"
  • Speaker : Dai Shiba
    JEM Utilization Center, Human Spaceflight Technology Directorate, Japan Aerospace Exploration Agency (JAXA)
  • SSY-02 "Outline of first mouse space experiment (MHU-1 mission) in "Kibo""
  • Speaker : Satoru Takahashi
    Transborder Medical Research Center, Fuclty of Medicine, University of Tsukuba
  • SSY-03 "Impact of microgravity on vestibular otolith system, a gravity sensor"
  • Speaker : Hironobu Morita
    Department of Physiology, Gifu University Graduate School of Medicine
  • SSY-04 "Application of space experiment to CMC research – Crystallization of middle molecule under microgravity-"
  • Speaker : Souichirou Kawazoe
    Astellas Pharma Inc., Pharmaceutical Technology, Pharmaceutical Science & Technology Labs.
  • Panel Discussion
    "Expectation and future of pharmacokinetics in space environment research"
  • Facilitator : Hiroshi Fushiki
    Astellas Pharma Inc., Drug Discovery Research,Analysis & Pharmacokinetic Research Labs.

Asia Joint Symposium

December 11 (Wed.) 9:30-11:45  Room B (2F Convention hall 200)

Intersection of the cutting-edge sciences in Asia

  • Organizer / Chair : Sumio Ohtsuki
    Department of Pharmaceutical Microbiology, Faculty of Life Sciences, Kumamoto University
  • JSY-01 "High degree of pharmacokenetic compatibihity exists between the five-herb mediceine XueBiJing and antibiotics comedicated in sepsisi care"
  • Speaker (CSSX) : Chuan Li
    State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China
  • JSY-02 "Effects of gut microbiota on the phamacokinetics of drugs"
  • Speaker (KSAP) : Hye Hyun Yoo
    College of Pharmacy, Hanyang University
  • JSY-03 "The potentials cancer stem cell-targeted therapeutic compounds for lung cancer treatment"
  • Speaker (PTST) : Pithi Chanvorachote
    Faculty of Pharmaceutical Sciences, Chulalongkorn University, Thailand
  • JSY-04 "Pharmaco-imaging analysis to visualize the drug distribution in anticancer drug development"
  • Speaker (JSSX) : Akinobu Hamada
    Division of Molecular Pharmacology, National Cancer Center Research Institute

The Predoctoral Researcher-Initiative Session(PRIS) 2019

December 10 (Tue.) 15:30-17:30  Room B (2F Convention hall 200)

Intersection & Challenge in Pharmacokinetics –Advanced Studies by The Next Generation Researchers –

  • Organizers : Ryuta Jomura
    Laboratory of Biopharmaceutics, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama
  •  Shizuka Hozuki
    Laboratory of Clinical Pharmacology and Pharmacometrics, Graduate School of Pharmaceutical Sciences, Chiba University
  •  Hiroki Kamioka
    Laboratory of Clinical Pharmacokinetics, Graduate School of Pharmaceutical Sciences, Takasaki University of Health and Welfare
  • Chair: Shizuka Hozuki
    Laboratory of Clinical Pharmacology and Pharmacometrics, Graduate School of Pharmaceutical Sciences, Chiba University
  • PSY-01(Education Lecture)"Challenge to application of Mass Spectrometry Imaging to Drug Discovery Research"
  • Speaker : Jun Tadano
    DMPK Group Ⅰ, Preclinical Research Unit, Sumitomo Dainippon Pharma Co., Ltd.
  • Chair: Hiroki Kamioka
    Laboratory of Clinical Pharmacokinetics, Graduate School of Pharmaceutical Sciences, Takasaki University of Health and Welfare
  • PSY-02 "Case study of in vivo evaluation for fraction absorbed of a low permeability compound without its radioisotope"
  • Speaker : Yuki Doi
    DMPK Research Laboratories, Mitsubishi Tanabe Pharma Corporation
  • Chair: Hiroshi Fujisawa
    Department of Biopharmaceutics, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences
  • PSY-03 "Functional evaluation of SLC and ABC transporters in brain microvascular endothelial cells derived from human iPS cells"
  • Speaker : Toshiki Kurosawa
    Laboratory of Drug Disposition & Pharmacokinetics, Faculty of Pharma Sciences, Teikyo University
  • Chair: Seiya Takemoto
    Drug Metabolism and Toxicology, Faculty of Pharmaceutical Sciences, Kanazawa University
  • PSY-04 "Human CYP3A mediated drug-drug interaction in CYP3A-humanized mice in vivo"
  • Speaker : Genki Minegishi
    Laboratory of Design and Drug Disposition, Graduate School of Pharmaceutical Sciences, Chiba University
  • Chair: Yukana Tomoda
    Laboratory of Molecular Pharmacokinetics, Graduate School of pharmaceutical sciences, The university of Tokyo
  • PSY-05 "Construction of hepatocytes cell-based MPT assessment system using galactose medium and enhanced mitochondrial ROS production under hypoxia/reoxygenation conditions"
  • Speaker : Yugo Ikeyama
    Laboratory of Biopharmaceutics, Graduate School of Pharmaceutical Sciences, Chiba University
  • Chair: Kosuke Tajima
    Laboratory of Pharmaceutics, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama
  • PSY-06 "Discovery of up- or down-regulated proteins in recurrent glioblastoma by SWATH-MS analysis"
  • Speaker : Shohei Kawarada
    Laboratory of Membrane Transport and Drug Targeting, Graduate School of Pharmaceutical Sciences, Tohoku University

Basic Course

December 12 (Thu.) 13:15-15:45  Room B (2F Convention hall 200)

Basic Pharmacokinetics: The required skills and capabilities as a DMPK researcher in the drug discovery and development

  • Organizer : Hideki Hirabayashi
    Drug Metabolism and Pharmacokinetics Research Laboratories,Takeda Pharmaceutical Company Limited
  • BC-01 "Basic Pharmacokinetics, which you can not ask about even now.
    - The three sacred treasures in Pharmacokinetic analysis -"
  • Lecture : Hideki Hirabayashi
    Drug Metabolism and Pharmacokinetics Research Laboratories, Takeda Pharmaceutical Company Limited
  • BC-02 "Clinical pharmacologist seeks contributions from non-clinical pharmacokineticist for efficient understanding of exposure-response relationship"
  • Lecture : Atsunori Kaibara
    Eli Lilly Japan K.K.